Oct 30, 2008 · Our study suggests that I-DmoI requires only 2 cations instead of 3 for DNA cleavage. The structure sheds light onto the basis of DNA binding, ...
Missing: Hydrolase- | Show results with:Hydrolase-
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These proteins are characterized by their ability to bind long DNA target sites (14–40 bp) and their tolerance of minor sequence changes in these sites. A ...
Missing: Hydrolase- | Show results with:Hydrolase-
Here, we report the crystal structure of the enzyme complexed to its DNA substrate and Ca2+ determined at 2.25 Å resolution. The structure shows the ...
Missing: Hydrolase- | Show results with:Hydrolase-
Nov 4, 2008 · gene targeting genetics protein–DNA interactions ... Hydrolysis of the phosphodiester bonds ... homing endonuclease I-Dmo-I in complex with its ...
Mar 3, 2014 · Homing endonucleases are highly specific DNA cleaving enzymes that are encoded within genomes of all forms of microbial life including phage ...
Missing: Hydrolase- | Show results with:Hydrolase-
Abstract. Sequence-specific endonucleases recognizing long target sequences are emerging as powerful tools for genome engineering. These endonucleases coul.
Missing: Hydrolase- | Show results with:Hydrolase-
Oct 26, 2004 · The I-SceI homing endonuclease enhances gene targeting by introducing double-strand breaks at specific chromosomal loci, thereby increasing ...
... ) CRYSTAL STRUCTURE OF LAGLIDADG MEGANUCLEASE I-PANMI WITH COORDINATED CALCIUM IONS | HYDROLASE-DNA COMPLEX, LAGLIDADG, HOMING ENDONUCLEASE, MEGANUCLEASE.
-. Basic information ; DNA endonuclease I-CeuI; I-CeuI DNA target site; I-CeuI DNA target site, complementary strand. Details · Hydrolase/DNA / homing ...
gene expression, and DNA repair. In many cases, this interaction involves both the recognition of a particular. DNA site and the catalysis of a bio.